Endocrine Abstracts

Macroprolactin is a complex of prolactin with immunoglobulin appearing to have limited biological activity, partly due to failure of this high-molecular weight complex to cross capillary walls.Macroprolactinaemia is a common phenomenon, it is thus important to identify this condition in order to avoid unnecessary investigations and treatment. Although the presence of macroprolactin can be confirmed by gel filtration chromatography, this is time consumin...